Abstract Background Diabetes-associated cognitive impairment (DACI) poses a significant challenge to the self-management of diabetes, markedly elevating the risk of adverse complications.A burgeoning body of evidence implicates microglia as a central player in the pathogenesis of DACI.Methods We utilized proteomics to identify potential biomarkers
The insulin receptor (IR) presents by alternative splicing two isoforms: IRA and IRB.The differential physiological and pathological role of both isoforms is not completely known, and it is determinant the different binding affinity for insulin-like growth factor.IRB is more abundant in adult tissues and it exerts mainly the metabolic actions of in
The Flood Damage Database HOWAS 21 contains object-specific flood damage data resulting from fluvial, pluvial 8 Channel LOC and groundwater flooding.The datasets incorporate various variables of flood hazard, exposure, vulnerability and direct tangible damage at properties from several economic sectors.The main purpose of development of HOWAS 21 wa
Although an influenza vaccine has been available for 70 years, influenza virus still causes seasonal epidemics and worldwide pandemics.Currently available vaccines elicit strain-specific antibody responses to the surface haemagglutinin (HA) and neuraminidase (NA) proteins, but these can be ineffective against serologically-distinct viral variants a
In Iranian Civil Law.like in Islamic Jurisprudence, in addition to puberty, the maturity is necessary in order to have capacity for carrying out transaction.The age Morgiel Gherkins in Brine of puberty is defined in jurisprudence; however, there is no specific age of maturity.Before the revolution in Iran , Article 1210 of the Civil Code determined